SEREN5 is a transnational project of National Contact Points in Horizon Europe, Europe’s biggest Research and Innovation programme. The main aim of SEREN5 is to improve and professionalise the skills of the Cluster 3 (CL3) National Contact Points (NCPs) across Europe, simplifying applicants’ access to Horizon Europe (HE) calls and raising the average quality of submitted proposals. Starting from the assumption that the NCP role is crucial in order to raise the participation in HE in terms of both quality and quantity, SEREN5 overall concept is that the CL3 NCP community requires knowledge, skills, competences and a proven comprehensive suite of tools to convey a message in a multicultural and multi-disciplinary environment such the one that characterises Cluster 3 and to effectively support its broad based constituency. Therefore, the project is based on three pillars: (i) NCPs capacity building and competence development, (ii) development of targeted and high quality services (events and tools) for CL3 applicants and stakeholders , (iii) CL3 community building and general mainstreaming of CL3 NCPs in Horizon Europe.